Articles | Volume 20, issue 9
https://doi.org/10.5194/acp-20-5197-2020
https://doi.org/10.5194/acp-20-5197-2020
Research article
 | 
04 May 2020
Research article |  | 04 May 2020

Characterization and comparison of PM2.5 oxidative potential assessed by two acellular assays

Dong Gao, Krystal J. Godri Pollitt, James A. Mulholland, Armistead G. Russell, and Rodney J. Weber

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Latest update: 21 Feb 2024
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Short summary
This study provides a direct intercomparison between two assays for quantifying oxidative potential (OP) of ambient particles: the synthetic respiratory-tract-lining fluid (RTLF) assay and the dithiothreitol (DTT) assay. The results suggest that the DTT assay and the ascorbic acid depletion in RTLF are associated with organic species, transition metal ions, and antagonistic interactions between species. The glutathione depletion in RTLF is strongly dependent on water-soluble copper.
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