This manuscript presents a study investigation of the temperature dependence of secondary organic aerosol formation and aging from mixtures of isoprene and α-pinene at different temperatures. The authors use AIDA chamber experiments, detailed molecular composition, and implement the results in a chemical transport model. The study addresses an important question: how tropospheric temperature influences SOA formation pathways and particle aging, particularly in systems involving multiple biogenic precursors. Most laboratory studies are conducted near room temperature, so the systematic exploration of temperatures spanning much of the troposphere is actually very good and very important.

Overall, the manuscript is very good, well written and very interesting for the scientific community. The combination of chamber measurements, molecular characterization, and modelling is a particular strength.

Overall, I believe the manuscript is suitable for publication in ACP.

Minor comments

The manuscript states that the PMCAMx simulations cover 5 June – 8 July 2012 during the PEGASOS campaign. However, Figure 7 appears to refer to measurements during June–July 2019, which is inconsistent with the PEGASOS campaign timeline. I belive that the right time is 2012.

The chamber experiments are conducted at relatively high precursor concentrations (tens of ppb VOC and several hundred ppb O3). That is very typical for chamber studies, however those conditions can change radical chemistry, oligomer formation and SOA yields. It would be nice to see a deeper discussion on how these conditions differ from typical atmosphere.