We examined the links between the El Niño–Southern Oscillation (ENSO) and tropospheric ozone (O₃) using model data. Our results show that ENSO impacts on tropospheric O₃ are mainly found over oceans, while the signature of ENSO over continents is largely unclear. These impacts in the midlatitude regions over the Southern Hemisphere may be more significant than previously known. The responses of O₃ to ENSO are weak in the middle troposphere and stronger in the upper and lower troposphere.