Articles | Volume 18, issue 3
Atmos. Chem. Phys., 18, 2329–2340, 2018
https://doi.org/10.5194/acp-18-2329-2018
Atmos. Chem. Phys., 18, 2329–2340, 2018
https://doi.org/10.5194/acp-18-2329-2018

Research article 16 Feb 2018

Research article | 16 Feb 2018

Evaluating the mutagenic potential of aerosol organic compounds using informatics-based screening

Stefano Decesari et al.

Download

Interactive discussion

Status: closed
Status: closed
AC: Author comment | RC: Referee comment | SC: Short comment | EC: Editor comment
Printer-friendly Version - Printer-friendly version Supplement - Supplement

Peer-review completion

AR: Author's response | RR: Referee report | ED: Editor decision
AR by Stefano Decesari on behalf of the Authors (27 Oct 2017)  Author's response    Manuscript
ED: Referee Nomination & Report Request started (17 Nov 2017) by Athanasios Nenes
RR by Anonymous Referee #1 (24 Nov 2017)
RR by Anonymous Referee #2 (27 Nov 2017)
ED: Publish as is (29 Dec 2017) by Athanasios Nenes
Download
Short summary
Particulate matter (PM) chemical composition includes thousands of individual organic compounds that have never been tested for their toxicological potential. Computational (in silico) screenings represent a promising approach to identify new target compounds for more in-depth toxicological analyses. We provide here a proof-of-concept evaluation based on ca. 100 aerosol organic compounds. Reliable toxicological predictions were obtained for more than 80 % of them.
Altmetrics
Final-revised paper
Preprint