Articles | Volume 17, issue 19
Research article
06 Oct 2017
Research article |  | 06 Oct 2017

Light-induced protein nitration and degradation with HONO emission

Hannah Meusel, Yasin Elshorbany, Uwe Kuhn, Thorsten Bartels-Rausch, Kathrin Reinmuth-Selzle, Christopher J. Kampf, Guo Li, Xiaoxiang Wang, Jos Lelieveld, Ulrich Pöschl, Thorsten Hoffmann, Hang Su, Markus Ammann, and Yafang Cheng


Interactive discussion

Status: closed
Status: closed
AC: Author comment | RC: Referee comment | SC: Short comment | EC: Editor comment
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Peer-review completion

AR: Author's response | RR: Referee report | ED: Editor decision
AR by Hannah Meusel on behalf of the Authors (09 Aug 2017)  Author's response    Manuscript
ED: Referee Nomination & Report Request started (18 Aug 2017) by Alexander Laskin
RR by Anonymous Referee #2 (03 Sep 2017)
ED: Publish as is (03 Sep 2017) by Alexander Laskin
Short summary
In this study we investigated protein nitration and decomposition by light in the presence of NO2 via flow tube measurements. Nitrated proteins have an enhanced allergenic potential but so far nitration was only studied in dark conditions. Under irradiated conditions we found that proteins predominantly decompose while forming nitrous acid (HONO) an important precursor of the OH radical. Unlike other studies on heterogeneous NO2 conversion we found a stable HONO formation over a long period.
Final-revised paper