Articles | Volume 23, issue 14
https://doi.org/10.5194/acp-23-7859-2023
https://doi.org/10.5194/acp-23-7859-2023
Technical note
 | 
17 Jul 2023
Technical note |  | 17 Jul 2023

Technical note: Improved synthetic routes to cis- and trans-(2-methyloxirane-2,3-diyl)dimethanol (cis- and trans-β-isoprene epoxydiol)

Molly Frauenheim, Jason D. Surratt, Zhenfa Zhang, and Avram Gold

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Latest update: 20 Nov 2024
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Short summary
We report synthesis of the isoprene-derived photochemical oxidation products trans- and cis-β-epoxydiols in high overall yields from inexpensive, readily available starting compounds. Protection/deprotection steps or time-consuming purification is not required, and the reactions can be scaled up to gram quantities. The procedures provide accessibility of these important compounds to atmospheric chemistry laboratories with only basic capabilities in organic synthesis.
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