Dear authors,
I decided to accept your publication, subject to minor revisions.

1) First of all I suggest to summarize your results per experiment and region in a Table, to aid the synthesis of results.
2) I further noticed that the Figure captions are often rather short and difficult to understand. Below I give some suggestions for improvements.


Figure 1: Please mention what is meant with 'summer' concentrations.
I assume June-July-August, 24 hours average.

In Figure 2 I do not see any bounding boxes in Africa. Are the parameters 24 hour averaged?

Table S1: explain the meaning of the parameters in Table description.

Figure S2: I assume this is the regression of the median of the six member model ensemble.Please mention in the Figure caption.

Figure S3: spell out IPE in caption, and F-scheme.

Figure S5. Explain in caption what is done with the information on boxes. Significance is based on what?

Figure S8. Not clear what is meant with meteorological feedback to IPE. Some additional info
(e.g. feedback due to higher temperatures) would help the reader.

Main text:
p. 8 l. 17; reasonably reproduces spatial patterns.
p. 10 l. 28 this sentence is confusing (negative in conjunction with the plus sign). I assume you mean negative changes of 0.9 and 0.7 due to reductions of isoprene emissions under high ozone.

Congratulations with the manuscript.