During spring 2020 a German research consortium performed the airborne BLUESKY measurement campaign, using the HALO and DLR Falcon aircraft, to investigate the atmospheric composition changes associated with the COVID-19 lockdown. Comprehensive atmospheric chemistry, aerosol, and cloud measurements were performed with the two aircraft, from the boundary layer to the lower stratosphere during 20 scientific flights over Europe and the North Atlantic. Many groups participated in the campaign (DLR Oberpfaffenhofen, three departments of the MPI for Chemistry, Mainz, University of Frankfurt, KIT Karlsruhe, FZ Jülich). The measurement data are unique and are supplemented by satellite remote sensing data and numerical model simulations. The data analysis also involves comparison with measurement data from many pre-lockdown aircraft campaigns and long-term projects (e.g. CARIBIC). A subject of special interest is the impact of aircraft emissions on atmospheric composition, as the lockdown was associated with a 70–90% reduction of air traffic.